Loona/Relationships

Blitzo
Blitzo is Loona's boss and adoptive father and has been since she was "almost 18". He has a father-daughter relationship with her as he enables her actions, and at times when he defends her, she smiles and agrees to his defense. She is also shown to appreciate Blitzo's sense of humor, especially if it's at Moxxie's expense since she was seen stifling a laugh when the former made a joke of the latter's dick size.

Despite this, she is still easily tempered when he cuddles her and was unappreciative when she received what she wanted as a gift for her adoption anniversary. She also is grossed out when he offers her a treat and then eats it himself and doesn't like it when Blitzo is overprotective of her (which is implied to be the main reason he made her the company's receptionist and rarely lets her go into the field despite being a very skilled fighter herself).

In the episode, "Spring Broken", Loona almost calls Blitzo "dad" when he states her looks are fine, but catches herself and calls him by name. Later, she and Blitzo get into a heated argument which ends with her insulting Blitzo and hurting his feelings. Realizing this, she does try to apologize but he storms off. As the episode neared it's end, Blitzo, as Loona guessed, appears to have moved on. It currently remains unknown if his and Loona's fight had negatively affected him and is just trying to hide it.

In "Truth Seekers", it has been shown that Loona respects Blitzo enough to do whatever he says when he is serious. When Blitzo ordered her to close the portal to Hell after Moxxie had been tranquilized by Agents 1 and 2, she does so without a second of thought due to his strict tone and lack of profanity. When Blitzo realized Loona had come along with Millie to save him and Moxxie, Blitzo was very concerned about his daughter's safety but became very proud of her when he saw her fighting off the agents and kissed her in the cheek, much to her chagrin.

Moxxie
Moxxie is one of Loona's colleagues. They seem to strongly dislike each other and she often pokes fun of his weight and his marital status. She also seems to enjoy seeing Moxxie suffer since she was seen watching something on her phone that shows him being killed in multiple ways and snickered when Blitzo made a joke about the size of the latter's penis. When Loona had apparently made a mistake about who their target was, Moxxie did not hesitate to insult Loona, calling her a drug addict among other things but she simply flipped him the bird.

She does show some willingness to help him with work when he was struggling with the idea of killing an "innocent family" by coming up with sinful backstories for the people in the photo she was holding.

In "Truth Seekers", Moxxie awkwardly greeted Loona when he realized she had come along to rescue them and had taken down Agent Two but he went ignored and Loona grinned when Blitzo stepped on Moxxie for no reason.

Millie
Millie is one of Loona's colleagues. They both dislike each other and neither bothers to hide it despite Loona being Millie's boss' daughter. In a flashback during the pilot episode, Loona once ignored Millie's calls for help after a stabbing. Millie can be seen flipping Loona off after Loona insults Moxxie while she snarled at Millie.

However, they both seem to tolerate each other enough to work together on missions (if Loona cares enough, that is). Millie usually refers to Loona as "our Hellhound" or "[Blitzo's] Hellhound", which irritates Loona and seems to imply that Millie thinks of Loona as a lesser being compared to her due to Loona being a Hellhound and Millie an imp, which is ironic since both their species are in the lowest-ranking tier of the hierarchy system. Millie is most likely only joking though.

In "Truth Seekers" Loona does show some form of concern when Millie cries after Moxxie is captured along with Blitzo by Agent One and Two and tries to warn her that going after them was going to be dangerous but is forced to give in to Millie's demands and the two women are forced to work together in infiltrate D.H.O.R.K.S. and rescue their boss and co-worker. Loona and Millie work well together and Loona kind of complimented Millie, saying that she is quite agile yet also calling Millie an "old lady" despite Millie's protests that she is only around five years older than Loona and together they manage to rescue Blitzo and Moxxie.

Stolas
Loona is only ever seen communicating to Stolas via phone, but it is presumed that she thinks negatively of him, calling him a “clingy rich asshole”.

In "Truth Seekers", Stolas saved her along with Blitzo, Moxxie and Millie while Loona seemed somewhat impressed by Stolas' rather frightening entrance and appeared to have recorded it with her phone.

Eddie
The only reason why Loona refrained from attacking Eddie even more was because, at the time, the company still was not sure if he was the right target. However, her apathy towards him turned into hatred after he insulted her by claiming to be a cat person, thus striking a nerve. She did not hesitate to help disembody his carcass after finding out that he was the right target, and seemed somewhat satisfied at his death.

Vortex
Loona met Vortex through Blitzo's rivalry with Verosika and immediately became smitten with him. Her attraction to him makes her awkward, but that doesn't stop them from forming a connection in a short span of time. Vortex treats her in a friendly manner, and finds some of her actions cute or funny, as shown from his joke of recreating her introduction to him. The two then became somewhat friends, as Vortex didn’t mind her company and didn’t view her (or her loyalties) in the same negative views as his employer. She hoped this would lead to them dating, but soon learns that Vortex already has a girlfriend, much to her disappointment. Whether or not her crush on him still exists because of this is unknown.